Pure Encapsulations

Pure Encapsulations Liquid B-12, Methylcobalamin is an activated, highly bioavailable form of vitamin B12, which acts as the principal circulating form of cobalamin in the body. In general, vitamin B12 works with folate to promote red blood cell formation. Additionally, vitamin B12 is an important cofactor for energy metabolism. One vitamin B12-dependent enzyme is methyl malonyl-CoA mutase, which is involved in the formation of succinyl-CoA, a key Krebs cycle intermediate. Vitamin B12 is also a vital component of the methionine synthase pathway.

Pure Encapsulations GI Fortify Powder, G.I. Fortify provides far-reaching support for constipation. Psyllium, or Plantago ovata, is a valued source of soluble fiber. Soluble fiber absorbs water to form a gel, increasing stool volume when taken with appropriate amounts of water to support larger and softer stools for healthy bowel movements. As the bulk moves through the intestine, it also helps to collect and eliminate other waste and toxins from the intestinal walls. Soluble fiber is fermented slowly in the colon by intestinal microflora, which further helps increase fecal mass. The fermentation process produces short-chain fatty acids (SCFAs), which have protective effects for healthy colon cell function as they are extremely important energy sources for the colon and may regulate colonic transit. Furthermore, SCFAs keep the intestinal environment acidic, providing optimal conditions for a healthy intestinal microflora. Flax is an additional source of soluble fiber, and also contains fatty acids and lignans. G.I. Fortify also contains the amino acid l-Glutamine, plus a combination of deglycyrrhizinated licorice (DGL), aloe, slippery elm, and marshmallow root. Additionally, it includes an equal proportion of three fruit extracts, Terminalia chebula, Terminalia bellirica and Emblica Officinalis, which has a long traditional history of use in the Ayurvedic medicine Triphala, literally translated as “three fruits”.

Pure Encapsulations Glucosamine & Chondroitin with MSM, Glucosamine + Chondroitin with MSM offers glucosamine HCl and chondroitin sulfate, combined with sulfur-containing methylsulfonylmethane (MSM) to provide an enhanced spectrum of nutrients for optimal joint comfort. Glucosamine promotes the synthesis of glycosaminoglycan chondroitin sulfate. Research has indicated that glucosamine HCl supports healthy cartilage integrity, in part by maintaining healthy matrix metalloproteinase (MMP) enzyme activity. Chondroitin sulfate plays a key role in the development of cartilage by promoting the synthesis of cartilage-forming molecules known as proteoglycans. In addition, sulfur from MSM helps maintain the structure and integrity of proteoglycans. Several studies have indicated that chondroitin sulfate has positive effects on joint mobility and comfort. Additionally, a recent randomized, double-blind, placebo-controlled trial revealed that MSM also promotes joint comfort and function.

Pure Encapsulations Ubiquinol-QH, Ubiquinol is the active antioxidant form of CoQ10, which is also known as ubiquinone. Ubiquinol comprises the majority of the ubiquinone/ubiquinol pool in the plasma of healthy young subjects, making it especially important for older individuals, those who experience greater levels of oxidative or physical stress, or individuals who appear not to respond to regular CoQ10 supplementation (possibly due to poor conversion of CoQ10 to ubiquinol in the body). Research suggests that it may also be more readily absorbed than the ubiquinone form. In the body, the enzymatic conversion of ubiquinone to ubiquinol in the mitochondria is a key step in the electron transport chain and the manufacture of ATP. In addition, clinical trials have reported that ubiquinol maintains cardiovascular health by supporting healthy ejection fraction and mitral valve function. CoQ10 also helps reduce the frequency of migraine headaches and associated symptoms when taken as a prophylactic. It acts by decreasing oxidative stress in neurons and maintaining neuronal and mitochondrial function. In a randomized, placebo-controlled trial involving adults with a history of migraines, daily supplementation with 150 mg of CoQ10 for three months reduced the number of days with a headache by over 50% in 61% of participants.
Kaneka QH™ is a trademark of Kaneka Corporation
The use of ascorbyl palmitate in the formulation is covered by U.S. Patent 6,740,338.

Magnesium citrate is a highly bioavailable form of magnesium that supports the metabolism of macronutrients and energy production. While normal magnesium levels may lessen the perception of exertion during exercise, suboptimal levels can occur after the loss of fluids, including prolonged sweating, which can compromise performance. Magnesium is an essential bone matrix mineral that promotes healthy bone metabolism. A trial involving 2,038 older individuals indicated that higher intakes of magnesium were positively associated with bone mineralization for certain subjects. Magnesium also plays essential roles in maintaining healthy muscle contractile function. As magnesium regulates calcium channels, it may have an important role in controlling cramping. Several clinical trials have found that magnesium supports muscle function during intense exercise and helps to lessen nighttime leg cramps.

Liposomal Glutathione offers enhanced absorption liposomal glutathione for powerful antioxidant support. Glutathione is a key component of the antioxidant system, which protects the body from free radicals at the cellular level. It is found in virtually every cell of the body and plays a critical role in proper cell function. The highest concentration of glutathione is found in the liver, where it offers antioxidant support for liver tissue protection and p450 phase II detoxification pathways, a possible source of reactive oxygen species. The purified phosphatidylcholine delivery system offers natural liposomal formation due to the hydrophobic and hydrophilic nature of phospholipids. This liposomal form protects glutathione bonds from the degradation that can occur in digestion and has demonstrated superior antioxidant support when compared to control treatments.

Ingredients
AMT
%DV
BioGlute™
proprietary blend of glutathione and essential phospholipids providing:
375 mg
-
glutathione
250 mg
-
phospholipid complex
125 mg
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Other

FocusPlus was developed by Pure Encapsulations in conjunction with Dr. James Greenblatt as part of the Integrative Mental Health Series, a line of products based on scientific findings and decades of clinical experience. DopaPlus is formulated to support daily cognitive functioning, including focus, stamina, memory and attention. It provides rhodiola, which also helps relieve symptoms of stress, such as mental fatigue and sensation of weakness. Also critical to each formulation in the Integrative Mental Health Series is the inclusion of a vitamin B6, zinc and Metafolin® L-5-MTHF cofactor complex to support nutrient metabolism; L-5MTHF is the form of folate that easily crosses the bloodbrain barrier. Folate and vitamin B6 are particularly important in amino acid metabolism, including the metabolism of tyrosine.
Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany.

Pure Tranquility l iquid offers a great-tasting, convenient combination of neurotransmitters, including GABA, plus Suntheanine® l-Theanine to support relaxation. GABA is one of the main inhibitory neurotransmitters in the body, which act to calm the nervous system. Suntheanine® is a patented, pure form of l-Theanine, a unique amino acid originally found in tea. Both GABA and l-Theanine have been shown to enhance alpha wave production in the brain, promoting relaxation and moderating stress. In an open trial, GABA promoted alpha waves and moderated beta waves within one hour of administration. In a preliminary study, l-Theanine enhanced alpha wave production in the occipital and parietal regions of the brain, an indicator of relaxation, without causing drowsiness. l-Theanine has also been shown to moderate the effects of caffeine on the central nervous system, further demonstrating its role in promoting relaxation.
Suntheanine® is a registered trademark of Taiyo International, Inc.