Pure Encapsulations

Pure Encapsulations Liquid B-12, Methylcobalamin is an activated, highly bioavailable form of vitamin B12, which acts as the principal circulating form of cobalamin in the body. In general, vitamin B12 works with folate to promote red blood cell formation. Additionally, vitamin B12 is an important cofactor for energy metabolism. One vitamin B12-dependent enzyme is methyl malonyl-CoA mutase, which is involved in the formation of succinyl-CoA, a key Krebs cycle intermediate. Vitamin B12 is also a vital component of the methionine synthase pathway.

Liposomal Glutathione offers enhanced absorption liposomal glutathione for powerful antioxidant support. Glutathione is a key component of the antioxidant system, which protects the body from free radicals at the cellular level. It is found in virtually every cell of the body and plays a critical role in proper cell function. The highest concentration of glutathione is found in the liver, where it offers antioxidant support for liver tissue protection and p450 phase II detoxification pathways, a possible source of reactive oxygen species. The purified phosphatidylcholine delivery system offers natural liposomal formation due to the hydrophobic and hydrophilic nature of phospholipids. This liposomal form protects glutathione bonds from the degradation that can occur in digestion and has demonstrated superior antioxidant support when compared to control treatments.

Ingredients
AMT
%DV
BioGlute™
proprietary blend of glutathione and essential phospholipids providing:
375 mg
-
glutathione
250 mg
-
phospholipid complex
125 mg
-
Other

Pure Encapsulations Liver G.I Detox, Liver-G.I. Detox supports the body's natural hepatic detoxification process by providing nutrients and botanical extracts, such as milk thistle and methionine, that promote liver function. Silymarin, a bioactive in milk thistle, is a heat protectant and is considered one of the most potent inducers of phase II detoxification enzyme activity. This highly active botanical also protects the liver from free radical damage, supports glutathione concentrations and promotes superoxide dismutase activity. Provided alongside the amino acids glutamine, glycine and taurine, methionine is a lipotropic compound that enhances healthy hepatic function by supporting lipid metabolism and glutathione concentration. It also supports several detoxification pathways in the liver to neutralize toxins. Artichoke extract promotes healthy bile flow, aiding the digestive process by optimizing nutrient utilization. Liver-G.I. Detox also provides the celebrated plant's curcumin and broccoli, along with N-Acetyl-L-Cysteine (NAC), alpha-lipoic acid and chlorella, the most studied “green food.”

Magnesium citrate is a highly bioavailable form of magnesium that supports the metabolism of macronutrients and energy production. While normal magnesium levels may lessen the perception of exertion during exercise, suboptimal levels can occur after the loss of fluids, including prolonged sweating, which can compromise performance. Magnesium is an essential bone matrix mineral that promotes healthy bone metabolism. A trial involving 2,038 older individuals indicated that higher intakes of magnesium were positively associated with bone mineralization for certain subjects. Magnesium also plays essential roles in maintaining healthy muscle contractile function. As magnesium regulates calcium channels, it may have an important role in controlling cramping. Several clinical trials have found that magnesium supports muscle function during intense exercise and helps to lessen nighttime leg cramps.

Pure Encapsulations GI Fortify Powder, G.I. Fortify provides far-reaching support for constipation. Psyllium, or Plantago ovata, is a valued source of soluble fiber. Soluble fiber absorbs water to form a gel, increasing stool volume when taken with appropriate amounts of water to support larger and softer stools for healthy bowel movements. As the bulk moves through the intestine, it also helps to collect and eliminate other waste and toxins from the intestinal walls. Soluble fiber is fermented slowly in the colon by intestinal microflora, which further helps increase fecal mass. The fermentation process produces short-chain fatty acids (SCFAs), which have protective effects for healthy colon cell function as they are extremely important energy sources for the colon and may regulate colonic transit. Furthermore, SCFAs keep the intestinal environment acidic, providing optimal conditions for a healthy intestinal microflora. Flax is an additional source of soluble fiber, and also contains fatty acids and lignans. G.I. Fortify also contains the amino acid l-Glutamine, plus a combination of deglycyrrhizinated licorice (DGL), aloe, slippery elm, and marshmallow root. Additionally, it includes an equal proportion of three fruit extracts, Terminalia chebula, Terminalia bellirica and Emblica Officinalis, which has a long traditional history of use in the Ayurvedic medicine Triphala, literally translated as “three fruits”.

Pure Encapsulations Glucosamine & Chondroitin with MSM, Glucosamine + Chondroitin with MSM offers glucosamine HCl and chondroitin sulfate, combined with sulfur-containing methylsulfonylmethane (MSM) to provide an enhanced spectrum of nutrients for optimal joint comfort. Glucosamine promotes the synthesis of glycosaminoglycan chondroitin sulfate. Research has indicated that glucosamine HCl supports healthy cartilage integrity, in part by maintaining healthy matrix metalloproteinase (MMP) enzyme activity. Chondroitin sulfate plays a key role in the development of cartilage by promoting the synthesis of cartilage-forming molecules known as proteoglycans. In addition, sulfur from MSM helps maintain the structure and integrity of proteoglycans. Several studies have indicated that chondroitin sulfate has positive effects on joint mobility and comfort. Additionally, a recent randomized, double-blind, placebo-controlled trial revealed that MSM also promotes joint comfort and function.

Pure Encapsulations Ubiquinol-QH, Ubiquinol is the active antioxidant form of CoQ10, which is also known as ubiquinone. Ubiquinol comprises the majority of the ubiquinone/ubiquinol pool in the plasma of healthy young subjects, making it especially important for older individuals, those who experience greater levels of oxidative or physical stress, or individuals who appear not to respond to regular CoQ10 supplementation (possibly due to poor conversion of CoQ10 to ubiquinol in the body). Research suggests that it may also be more readily absorbed than the ubiquinone form. In the body, the enzymatic conversion of ubiquinone to ubiquinol in the mitochondria is a key step in the electron transport chain and the manufacture of ATP. In addition, clinical trials have reported that ubiquinol maintains cardiovascular health by supporting healthy ejection fraction and mitral valve function. CoQ10 also helps reduce the frequency of migraine headaches and associated symptoms when taken as a prophylactic. It acts by decreasing oxidative stress in neurons and maintaining neuronal and mitochondrial function. In a randomized, placebo-controlled trial involving adults with a history of migraines, daily supplementation with 150 mg of CoQ10 for three months reduced the number of days with a headache by over 50% in 61% of participants.
Kaneka QH™ is a trademark of Kaneka Corporation
The use of ascorbyl palmitate in the formulation is covered by U.S. Patent 6,740,338.

MicroActive® CoQ10 is a water-soluble, submicron particle-sized CoQ10 generated through a patented process that complexes each CoQ10 molecule with a beta-cyclodextrin molecule. CoQ10 is bound to the lipophilic end of the molecule, while the other end is hydrophilic, facilitating dispersion and transport. At the cellular surface, the complex dissociates, liberating a single CoQ10 molecule for efficient absorption. Clinical research indicates superior absorption compared to solubilized and crystalline CoQ10, with low inter-subject variance. The actions of CoQ10 are particularly supportive of tissues that require a lot of energy, such as the heart muscle. CoQ10 provides multifunctional support for cardiovascular health through different mechanisms, including mitochondrial and antioxidant support. Research indicates that CoQ10 supports heart muscle function and healthy cellular oxygen utilization by promoting energy production as a core component of cellular respiration. Furthermore, it acts as an antioxidant, providing protection from free radicals and helping to maintain the integrity of cellular membranes. PQQ (pyrroloquinoline quinone) is a novel redox cofactor naturally present in vegetables and in the human body, including breast milk. BioPQQ® is manufactured in Japan using a patented natural fermentation process, and has been studied in numerous mechanistic investigations as well as a recent double-blind, placebo-controlled trial.
BioPQQ® is a trademark of MGC (Japan)

SeroPlus was developed by Pure Encapsulations in conjunction with Dr. James Greenblatt as part of The Integrative Mental Health Series, a line of products based on scientific findings and decades of clinical experience. SeroPlus contains 5-HTP to support healthy mood balance by providing serotonin building blocks. By helping to form serotonin, 5-HTP balance serotonin function in the brain for emotional wellness. Also critical to each formulation in this series is the inclusion of vitamin B6, zinc and Metafolin® L-5-MTHF cofactors; L-5MTHF is the form of folate that easily crosses the blood-brain barrier. These nutrients are often depleted in individuals due to medications, inadequate diets and toxic environmental exposures, compromising the ability to properly metabolize nutrients. Along with zinc, vitamin B6 is a cofactor in amino acid metabolism, including the metabolism of 5-HTP into serotonin.
Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany.

• glucosamine sulfate1,500 mg.
• • (from crab, shrimp)
• BioCell Collagen^™ hydrolyzed collagen complex400 mg.
• • (chicken sternal cartilage)
• • providing (typical):
• • hydrolyzed collagen 60%
• l-proline (free-form)500 mg.
• l-lysine HCl500 mg.
• vitamin C (as ascorbic acid)200 mg.
• silica15 mg.
• • (from bamboo (bambusa spp.) extract (stem))
• devil's claw100 mg.
• • (harpagophytum procumbens) extract (root)
• • (standardized to contain 5% harpagosides)
• turmeric (curcuma longa) extract (root)100 mg.
• • (standardized to contain 95% curcuminoids)

Non-medicinal