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THORNE MELATON-5 60CAPS

Melatonin, the primary hormone of the pineal gland, acts as a powerful "chronobiotic," helping to maintain normal circadian rhythms.* In individuals having difficulty sleeping or with altered circadian rhythms, such as occur in jet lag and night shift work, supplementation with melatonin can help...

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Melatonin, the primary hormone of the pineal gland, acts as a powerful "chronobiotic," helping to maintain normal circadian rhythms.* In individuals having difficulty sleeping or with altered circadian rhythms, such as occur in jet lag and night shift work, supplementation with melatonin can help provide the resynchronization of those cycles, at amounts ranging from 0.3-8.0 mg.* Synthesis of melatonin from the amino acid tryptophan can be decreased by the aging process. Melatonin is a potent antioxidant.* Adequate melatonin levels have been reported to be a positive factor in cardiovascular, neuroendocrine, and bone health.*
Melatonin administration exerts a sedative-like effect in amounts of 0.3-5.0 mg.* When taken before onset of one's own melatonin secretion, even low amounts of melatonin can promote sleep.* Melatonin is thought to potentiate the effects of gamma-aminobutyric acid (GABA) via direct interaction with GABA receptors, thus resulting in relaxation.* Research indicates melatonin exerts sleep-promoting action by decreasing the time to fall asleep, improving the ability to stay asleep, and enhancing the depth of sleep.* Thorne's Melaton-1 supplies 1 mg of melatonin in each capsule. This potency is ideal for those individuals who may only require a low amount of melatonin to promote restful sleep or help maintain normal circadian rhythms.*

to accommodate those needing higher supplementation
synthesis of melatonin can be decreased by the aging process
results in little or no "hangover" effect on psychomotor performance after waking*
also available in 1-mg and 3-mg strengths
made without flowing agents that can inhibit bioavailability
Medicinal Ingredients:
Melatonin 5 mg
Non-Medicinal Ingredients:
Hypromellose (derived from cellulose) capsule, Microcrystalline Cellulose,  Calcium Laurate, and Silicon Dioxide.
Take 1 capsule one time daily at or before bedtime or as recommended by a health-care practitioner. Consult a health-care practitioner for use beyond 4 weeks.
Consult a health-care practitioner prior to use if you have a hormonal disorder, diabetes, liver or kidney disease, cerebral palsy, seizure disorders, migraine, depression and/or hypertension or if you are taking blood pressure or sedative/hypnotic medications. If symptoms persist continuously for more than 4 weeks (chronic insomnia), consult your health-care practitioner. Do not use if you are taking immunosupressive drugs. Do not drive or use machinery for 5 hours after taking melatonin. Do not use if you are pregnant or breastfeeding.

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