IB Care contains enterically coated peppermint, oregano, and caraway oils, all shown to have benefit for diverse gastrointestinal disturbances. Peppermint oil is known to influence gastric motility, accelerating early gastric emptying with an antispasmodic effect on the stomach. It also increases the relaxation time of the pyloric valve, decreases the resting pressure of the lower esophageal sphincter, and has synergistic benefit when combined with caraway oil, producing smooth muscle relaxation in the stomach and duodenum. Oregano oil has demonstrated antimicrobial effects against H. pylori, the primary cause of peptic ulcer disease and dyspepsia, as well as other GI pathogens.

Clinically, enterically coated preparations of these oils have demonstrated benefits in a number of clinical trials. Improvement has been shown for dyspepsia and symptoms such as pain, heaviness, and abdominal pressure in controlled trials, regardless of H. pylori status and even in those with significant epigastric pain. Additionally, enteric coated peppermint oil demonstrated clinical efficacy in a number of trials for irritable bowel syndrome, showing improvement in the majority of participants, and in both children and adults.